30/10/2026
THIS PATIENT DATA WAS GATHERED BY ROLL NO 14 BATCH 2023 AS PART OF HER COMPETENCE BASED LEARNING EVALUATION PORTFOLIO PREPARATION
THIS IS THE CASE OF 26F WITH FEVER 2 DAYS, BLEEDING NOSE AND GUM 1 DAY
*Demographics*
- *Age / Sex:* 26 years / Female
- *Occupation:* Construction worker
*Chief Complaints*
- Fever since 2 days
- Bleeding from nose & gums since 1 day
*History of Present Illness*
- Patient is G2 P1 A0 L1, 2 months pregnant.
- She has pain in legs since 16 years.
- She was asymptomatic 2 days ago, then she developed fever during evening.
- Fever is intermittent.
- Fever decreases when taking medications (Paracetamol).
- Fever is associated with headache, frontal.
- Fever increases with chills & rigors.
- Associated with pain in her legs.
- History of epistaxis & gingival bleeding since one day.
*History of Present Illness - Continued*
- History of pain in head 3 days ago
- History of vomiting - 3 episodes
- Bleeding occurs when brushing teeth
- Avoiding spicy food
*Negative History*
- No history of blood in urine
- No history of hematemesis
- No history of hemoptysis
- No history of shortness of breath
- No history of seizures
- No history of blood in stool
- No history of pain in joints
- No history of diarrhea
- No constipation
*Past History*
- History of open sewage system near her home
*Family History*
- Her daughter has fever since yesterday afternoon, gradually progressive, high grade, with chills & rigors
- No history of vomiting, loose stools, pain abdomen
- No history of DM in father
- No history of HTN / TB / Epilepsy / Asthma in family
- No history of bleeding disorders in family
*General Examination*
- Patient is conscious, coherent, cooperative - well oriented to time, place, person
- Moderately nourished
- *PICCLE:*
- *P - Pallor:* Absent
- *I - Icterus:* Absent
- *C - Cyanosis:* Absent
- *C - Clubbing:* Absent
- *L - Lymphadenopathy:* Absent
- *E - Edema:* Absent
*Vitals*
- *Temp:* Febrile
- *BP:* 120/60 mmHg
- *RR:* 20 bpm
- *PR:* 80 bpm
*Systemic Examination*
- *CVS:* S1 S2 present (+), No murmur
- *RS:* Normal Vesicular Breath Sounds (NVBS), No added breath sounds
- *CNS:* No Abnormality Detected (NAD)
*Complete Blood Count (CBC)*
- *Age / Sex:* 26 years / Female
- *Department:* General Medicine
Investigation | Result | Units | Biological Reference Interval
Hemoglobin | 12.5 | g/dL | M: 13.5 - 17.5, F: 12 - 15
TRBC Count | 3.9 | millions/cumm | M: 4.5 - 5.5, F: 3.5 - 5.0
Total WBC Count | 5,100 | cells/cumm | 4000 - 11000
Neutrophils | 85 | % | 40 - 80
Lymphocytes | 10 | % | 20 - 40
Eosinophils | 02 | % | 1 - 6
Monocytes | 03 | % | 2 - 10
Basophils | 00 | % | 0 - 2
PCV | 38.0 | % | M: 40 - 50, F: 36 - 44
MCV | 96.1 | fL | 80 - 98
MCH | 31.7 | pg | 27 - 33
MCHC | 33.0 | gm/dL | 32 - 36
Platelet Count | 72,000 | cells/cumm | 1.5 - 4.5 lakh/cumm
*Complete Blood Count (CBC)*
- *Age / Sex:* 26 years / Female
- *Department:* Obstetrics / Unit-III
Investigation | Result | Units | Biological Reference Interval
Hemoglobin | 12.9 | g/dL | M: 13.5 - 17.5, F: 12 - 15
TRBC Count | 4.0 | millions/cumm | M: 4.5 - 5.5, F: 3.5 - 5.0
Total WBC Count | 6,500 | cells/cumm | 4000 - 11000
Neutrophils | 87 | % | 40 - 80
Lymphocytes | 09 | % | 20 - 40
Eosinophils | 01 | % | 1 - 6
Monocytes | 03 | % | 2 - 10
Basophils | 00 | % | 0 - 2
PCV | 39.0 | % | M: 40 - 50, F: 36 - 44
MCV | 95.6 | fL | 80 - 98
MCH | 31.6 | pg | 27 - 33
MCHC | 33.1 | gm/dL | 32 - 36
Platelet Count | 1.1 | Lakhs/Cumm | 1.5 - 4.5 lakh/Cumm
Here is a clean, deidentified text version of the ultrasound report:
*Obstetric Ultrasound*
- *Referring Department:* Obstetrics
- *Study:* Ultrasound - Pregnancy
*Findings Visible:*
- Multiple ultrasound images showing an intrauterine gestational sac
- Fetal pole / embryo visualized within the sac
- Fetal cardiac activity visualized on Doppler trace
- Gestational age corresponding to *9 weeks 4 days* as per other parameters
*Note on Report:*
- Fetal sex was not disclosed, as per patient preference / protocol
*USG Early Pregnancy*
- *Age / Sex:* 26 years / Female
- *Referring Department:* Obstetrics
*Findings*
- Single live intrauterine gestation sac noted with Yolk sac, fetal pole are visualized.
- Cardiac activity present. FHR: 196 bpm
- CRL: 2.79 cm corresponding to 9 weeks 4 days.
- EDD: 29/05/2027.
- Cervical length: 3.5 cm.
- Maternal: Bilateral adnexa normal.
*Impression*
- Single live intrauterine gestation corresponding to 9 weeks 4 days gestational age
*Advice*
- Kindly correlate with clinical findings and other parameters.
*Declaration*
- I have neither detected nor disclosed the sex of the fetus of the pregnant woman to anybody. The pregnant woman before undergoing ultrasonography / image scanning declared that she does not want to know the sex of her fetus.
*Lab Report - Department of Microbiology*
- *Age / Sex:* 26 years / Female
- *Sample Type:* Serum
Investigation | Result | Reference Range
DENGUE NS 1 Antigen | POSITIVE | Not applicable
DENGUE IgM | Non - Reactive | Not applicable
DENGUE IgG | Non - Reactive | Not applicable
*Note*
1. This is only a screening test.
2. The test results to be confirmed with supplementary tests like ELISA/PCR.
*Lab Report - Microbiology*
*Malaria Parasite Test Report*
- *Age / Sex:* 26 years / Female
- *Sample Type:* Serum
Investigation | Result
MALARIA PARASITE PV | NON REACTIVE
MALARIA PARASITE PF | NON REACTIVE
*Method:* Immunochromatography test
*Lab Report - Department of Microbiology*
*Widal Test*
- *Age / Sex:* 26 years / Female
- *Sample Type:* Serum
Investigation | Result | Reference Range
S. Typhi "O" | 1:160 | ≥1:160 Significant Titre
S. Typhi "H" | 1:80 | ≥1:320 Significant Titre
S. Para Typhi A(H) | 1:20 | > 1:80 Significant Titre
S. Para Typhi B(H) | 1:20 | > 1:80 Significant Titre
*Method:* Slide Agglutination test.
*Note:*
1. A Positive WIDAL test may occur because of previous Typhoid infection, certain autoimmune diseases and non-specific fevers (Anamnestic reaction).
2. Rising titer in paired sera is significant.
Here is a set of Socratic questions tailored for medical students based on this clinical case report:
Clinical Presentation & History
* Pregnancy & Presentation: How does the physiological state of a 9-week pregnant patient (G2 P1 A0 L1) influence your differential diagnosis when evaluating acute febrile illness accompanied by bleeding manifestations?
* Symptom Timeline: The patient presented with a 2-day history of intermittent fever followed by a 1-day history of epistaxis and gingival bleeding. Why is the rapid onset of mucosal bleeding relative to the duration of the fever a critical warning sign?
* Epidemiological Clues: The history notes an "open sewage system near her home" and a daughter with a progressive high-grade fever with chills. How do household and environmental exposures alter your suspicion for vector-borne versus water-borne infectious diseases?
Investigations & Laboratory Findings
* Platelet Kinetics: The patient's platelet count is documented at 72,000 to 1.1 \text{ lakhs/cumm}. Given the bleeding manifestations, what phase of the disease process does this thrombocytopenia suggest, and at what threshold would prophylactic platelet transfusion typically be considered in a pregnant patient?
* Diagnostic Interpretation (Dengue): The Dengue NS1 Antigen test returned Positive, while Dengue IgM and IgG were Non-Reactive. What does an isolated positive NS1 antigen with negative IgM/IgG tell you about the window of infection?
* Confounding Serology: The Widal test showed a significant titer for S. Typhi "O" (1:160). How do you differentiate a true acute typhoid infection from a false-positive Widal test in an endemic region experiencing an acute viral illness like dengue (anamnestic reaction)?
Management & Complications
* Obstetric Monitoring: With the ultrasound confirming a single live intrauterine gestation at 9 weeks and 4 days (FHR 196 bpm), what unique maternal and fetal risks are introduced by acute dengue infection during the first trimester?
* Red Flag Monitoring: In a patient presenting with thrombocytopenia, epistaxis, gum bleeding, and vomiting, what clinical and laboratory parameters would prompt you to upgrade this diagnosis from uncomplicated dengue to severe dengue (dengue hemorrhagic fever / dengue shock syndrome)?














