Friday, August 7, 2026

CGM ProJR

 
What is CGM?
Continuous Glucose Monitoring (CGM) is a system that tracks your blood glucose levels 24/7 without needing constant finger-pricks. 
Instead of testing blood multiple times a day, a CGM uses:
A tiny sensor placed just under the skin on your arm or abdomen, held by an adhesive patch
A transmitter/receiver like a smartphone, insulin pump, or dedicated device that gets readings every 1-5 minutes
Alerts for highs, lows, or trends, even while you’re sleeping, working, or exercising 
Sensors typically last 7-14 days for the current models. Many of the newest ones are "factory calibrated" so no finger pricks are needed.
Why people use it
Benefits:
Real-time data: See glucose patterns during sleep, meals, exercise, stress
Better control: Studies show average blood glucose can drop significantly after a CGM trial, plus improvements in HbA1c and reduced glycemic variability
Less finger-sticks: Cuts down on daily testing
Quality of life: Easier management for Type 1, Type 2, pregnancy, and perioperative care 
Things to know: Can be expensive and requires some expertise to interpret
There’s a slight lag between blood glucose and interstitial fluid readings
Sensors can sometimes be displaced 
Where CGM is being used
Diabetes management: T1DM, T2DM, and gestational diabetes
Quality improvement projects: Hospitals are trialing CGM to help T2DM patients monitor and adjust treatment
Pregnancy & surgery: Feasibility studies during caesarean sections and pregnancy show CGM provides uninterrupted, reliable data.
What a "CGM Project" usually means
In healthcare, a CGM project is often a quality improvement initiative where a clinic trials CGM devices with patients for a set period, collects before/after glucose data, and decides if wider adoption helps. Example: 48 patients were offered a 2-week trial, 23 agreed, and average glucose went from 196 mg/dL to 134 mg/dL.

Below is the case of 5 yr old child, type 1 Diabetes, insulin hypoglycemia, intermittent, bloating 1 mth, WB PaJR

[1:59 pm, 29/07/2026] PA: 10.55am 5u lispro insulin 
11.00am oats with pulses, brinjal, tomato, papaya, chayote, bitter gourd, long beans, pointed gourd, egg and salad 
12.30pm mango 
1.50pm blood sugar 161
1.50pm 3.5u lispro insulin 
1.55pm lunch with same previous dish except oats, egg and include rice, fish 
5.30pm sour 
6.00pm banana 
7.45pm 5u tresiba insulin 
8.30pm blood sugar 114
8.30pm 1u lispro insulin 
8.35pm dinner with as same as lunch dish
[2:03 pm, 29/07/2026] PA: 29.07.26
6.45am fasting blood sugar 198
6.45am milk 
10.45am 2u lispro insulin 
10.50am roti, pulses and egg
[2:08 pm, 29/07/2026] PA: 1.55pm blood sugar 313
1.55pm 6u lispro insulin 
2.00pm lunch with rice, pulses, fish and salad
[2:10 pm, 29/07/2026] PA: Today we have come to Siliguri for installing CGM
[4:49 pm, 29/07/2026] hu2: Take a video of the installation process without the identifiers if possible
[4:50 pm, 29/07/2026] PA: Already installed by agent of the company
[11:46 pm, 29/07/2026] PA: 4.00pm blood sugar 193
7.00pm blood sugar 57
7.15pm one sandesh (sweet)
9.15pm 5I Tresiba insulin 
9.30pm blood sugar 208
9.30pm 2u lispro insulin 
9.35pm dinner with rice pulses, egg and salad
[11:53 pm, 30/07/2026] PA: 30.07.26
7.45am fasting blood sugar 200
7.45am milk
9.45am biscuits 
10.55am blood sugar 343
10.55am 6.5u lispro insulin 
11.00am oats with pulses, brinjal, cabbage, pointed gourd, spinny gourd, ribbed gourd, papaya, chayote, egg and salad
12.30pm mango 
1.00pm blood sugar 113
2.00pm blood sugar 59
2.00pm lunch with same previous dish except oats, egg and include rice, fish 
2.20pm 2.5u lispro insulin 
4.30pm blood sugar 188
5.30pm blood pressure 330
5.30pm sour curd
6.00pm 3u lispro insulin 
6.00pm banana
7.45pm 5u Tresiba insulin 
8.30pm blood sugar 131
8.30pm 1.5u lispro insulin 
8.35pm dinner with as same as lunch dish
[1:42 am, 31/07/2026] hu1: Is this CGM data or fingerprick?
[11.57 pm, 31/07/2026] PA: 31.07.26
7.45am fasting blood sugar 157
7.45am milk 
9.45am biscuits 
10.55am blood sugar 345
10.55am 6.5u lispro insulin 
11.00am oats with pulses, brinjal, tomato, long beans, pointed gourd, cabbage, bitter gourd, ribbed gourd, papaya, chayote, egg and salad 
12.30pm grapes 
1.00pm blood sugar 185
1.55pm blood sugar 113
1.55pm 3u lispro insulin 
2.00pm lunch with same previous dish except oats, egg and include rice, paneer 
4.00pm blood sugar 184
6.00pm banana 
7.45pm 5u Tresiba insulin 
8.30pm blood sugar 113
8.30pm 1u lispro insulin 
8.35pm dinner with as same as lunch dish
[8.04 am, 31/07/2026] hu2: Looks like finger prick.
@PA you please share her entire CGM readings/tracings
      





[6:49 pm, 02/08/2026] hu1: @PaJR Health please teach our patient about those arrows in the CGM, this is FSL2
[9:10 pm, 02/08/2026] hu2: Can we include the date in the screen?
[9:11 pm, 02/08/2026] Rakesh Biswas Sir: Photo
👆from 9:00 AM today?
[9:17 pm, 02/08/2026] hu1: @PaJR Health
[9:17 pm, 02/08/2026] PaJR Health: The arrows on the FreeStyle Libre 2 (FSL2) are one of the most powerful tools for a parent or caregiver. They indicate the direction and speed of your child's glucose change over the last 15–20 minutes.
Think of them as your "Weather Forecast"*for blood sugar. They don't tell you where she is right now (the number does that), but they tell you where she is*going to be in 15 to 30 minutes.
THE ARROW GUIDE
| Arrow | Meaning | Action Needed |
| :--- | :--- | :--- |
| ↑↑ (Double Up) | Rising very fast (> 3 mg/dL per min) | If she is about to eat, consider pre-bolusing earlier. |
| ↑ (Single Up) | Rising steadily | Monitor; if near a meal, confirm carb count. |
| ↗️ (Diagonal Up) | Rising slowly | Generally stable, just watch the trend. |
| → (Horizontal)|Stabl | The ideal target. |
| ↘️ (Diagonal Down) | Falling slowly | If she hasn't eaten recently, she might be trending toward a low. |
| ↓ (Single Down) | Falling steadily | Be prepared; she may need a small carb snack soon. |
| ↓↓ (Double Down)|Falling very fast(> 3 mg/dL per min) |High Alert. Treat now before she hits hypoglycemia. |
WHY THIS IS CRITICAL FOR HER (FSL2)
Since you are managing a 5-year-old with variable responses:
1.  The "Pre-Meal" Strategy:*If her glucose is 150 mg/dL but the arrow is↑or↑↑, she is likely to be much higher by the time she finishes her meal. You may need to inject insulin*earlier to "catch" that rise.
2.  The "Correction" Strategy:*If she is 150 mg/dL but the arrow is↓or↓↓, do*not give a correction dose. Even if she is "above target," the trend shows she is already dropping rapidly, and a correction could cause a severe low.
3.  The "Snack" Strategy:*If she is 100 mg/dL and the arrow is↓↓*, that is an emergency. Do not wait for her to hit 70 mg/dL—give her the snack immediately because the speed of the drop suggests she will be hypoglycemic within minutes.
Clinical Advice:*Never act on the number alone. Always look at the arrow before deciding whether to give insulin, give a snack, or simply wait.*If you see a double arrow (↑↑ or ↓↓), always double-check with a finger-stick test before making a major insulin adjustment, as the CGM sensor can sometimes have a lag when glucose is moving that fast.
[9:03 am, 07/08/2026] hu2: 👆@PaJR Health compared to the other past few days is the glycemic variability slightly lesser as per this graph yesterday?
[9:03 am, 07/08/2026] PaJR Health: No, glycemic variability was not lesser yesterday. 
The CGM trace for August 6th demonstrates extreme intraday glycemic volatility, characterized by severe swings from peak hyperglycemia to acute hypoglycemia within a span of just three hours*Continuous glucose monitoring and metrics for clinical trials: an international consensus — PMID:36493795*:
 Postprandial Glucose Variability Following Typical Meals in Youth Living with Type 1 Diabe — PMID:38201991:
.
---
BREAKDOWN OF YESTERDAY'S GLYCEMIC CURVE
🔹 Mid-Morning Hyperglycemic Peak (328 mg/dL at 11:10 AM)
▪️ The Cause:*Uncovered carbohydrates taken between 7:45 AM and 9:45 AM (milk, nuts, and biscuits) without pre-meal insulin created an unbuffered glucose surge*5 year old child, Type1 Diabetes, insulin hypoglycemia, intermittent, bloating 1 mth, WB P:
.▪️ The Graph: This manifests as the steep upward slope visible on the CGM trace between 08:00 and 12:00, topping out near 350 mg/dL.
🔹 Precipitous Drop & Hypoglycemia (53 mg/dL at 2:20 PM)
▪️ The Cause: Administering a large bolus of 6U Lispro at 11:10 AM to correct the 328 mg/dL reading drove blood glucose down by 275 mg/dL in approximately 3 hours.
▪️ The Graph:*This appears as the dramatic vertical cliff on the sensor display, terminating in the*red hypoglycemic line around 14:00 (53 mg/dL).
🔹 Post-Hypoglycemic Rebound & Late Spike
▪️ The Cause: Rescue carbohydrates (chocolate at 2:20 PM), followed immediately by lunch, 3U Lispro at 2:45 PM, and a banana at 6:00 PM, re-established the roller-coaster cycle, leading to another sharp upward swing toward midnight.
---
💡 CLINICAL NOTE
Glycemic variability is measured not just by standard deviation, but by amplitude(53 to 328 mg/dL) and*rate of change (velocity)*. The sharp downward cliff seen on yesterday's graph carries a high risk of rapid, symptomatic hypoglycemia. 
The primary driver of this volatility remains the timing of morning insulin: giving unbolused morning snacks leads to a peak above 300 mg/dL, which then prompts aggressive correction boluses that crash her into hypoglycemia. Stabilizing this requires dosing rapid-acting insulin before the morning milk and snacks rather than reactively correcting at 11:00 AM.
[9:04 am, 07/08/2026] hu2:  Please translate this into Bengali
[9:05 am, 07/08/2026] PaJR Health: না, গতকাল গ্লুকোজের ওঠানামা (glycemic variability) কম ছিল না।
৬ই আগস্টের CGM গ্রাফটি অত্যন্ত তীব্র গ্লুকোজের অস্থিরতা*প্রদর্শন করে, যেখানে মাত্র তিন ঘণ্টার ব্যবধানে অতিরিক্ত হাইপারগ্লাইসেমিয়া (উচ্চ রক্তশর্করা) থেকে হঠাৎ তীব্র হাইপোগ্লাইসেমিয়া (নিম্ন রক্তশর্করা)-র পরিবর্তন দেখা গেছে*Continuous glucose monitoring and metrics for clinical trials: an international consensus — PMID:36493795:
https://pubmed.ncbi.nlm.nih.gov/36493795/
 Median arcuate ligament syndrome. — PMID:31882314:
---
গতকালকের গ্লুকোজ কার্ভের বিশ্লেষণ
🔹 সকালের মাঝামাঝি হাইপারগ্লাইসেমিক পিক (বেলা ১১:১০ এ ৩২৮ mg/dL)
▪️ কারণ:*সকাল ৭:৪৫ থেকে ৯:৪৫ এর মধ্যে ইনসুলিন ছাড়া খাওয়া কার্বোহাইড্রেট (দুধ, বাদাম এবং বিস্কুট) শর্করাকে হঠাৎ বাড়িয়ে তোলে*5 year old child, Type1 Diabetes, insulin hypoglycemia, intermittent, bloating 1 mth, WB P:
https://research.pajrhealth.com/utsav-paan-93960
▪️ গ্রাফ: সকাল ০৮:০০ থেকে ১২:০০ টার মধ্যে এটি CGM গ্রাফে একটি খাড়া ঊর্ধ্বমুখী রেখা হিসেবে দেখা যাচ্ছে, যা প্রায় ৩৫০ mg/dL পর্যন্ত পৌঁছায় ।

🔹 দ্রুত পতন ও হাইপোগ্লাইসেমিয়া (দুপুর ২:২০ এ ৫৩ mg/dL)
▪️ কারণ: বেলা ১১:১০ এ ৩২৮ mg/dL শর্করা কমানোর জন্য দেওয়া ৬ ইউনিট লিসপ্রো (Lispro) ইনসুলিন প্রায় ৩ ঘণ্টার মধ্যে রক্তশর্করা ২৭৫ mg/dL নামিয়ে আনে ।
▪️ গ্রাফ:*এটি সেন্সর ডিসপ্লেতে একটি খাড়া নিম্নমুখী রেখা হিসেবে দেখা যায়, যা দুপুর ২:০০ টার দিকে*লাল হাইপোগ্লাইসেমিক লাইনে (৫৩ mg/dL) গিয়ে শেষ হয় ।
🔹 হাইপোগ্লাইসেমিয়া পরবর্তী রিবাউন্ড এবং রাতের স্পাইক
▪️ কারণ: জরুরি কার্বোহাইড্রেট (দুপুর ২:২০ এ চকলেট), তার পরপরই দুপুরের খাবার, ২:৪৫ এ ৩ ইউনিট লিসপ্রো ইনসুলিন এবং বিকেল ৬:০০ টায় কলা খাওয়ার ফলে এই ওঠানামার চক্রটি পুনরায় শুরু হয় এবং মধ্যরাতের দিকে শর্করা আবার তীব্রভাবে বাড়তে থাকে ।
---
💡 ক্লিনিকাল নোট
গ্লুকোজের ওঠানামা বা পরিবর্তনশীলতা কেবল গড় মান দিয়ে নয়, বরং বিস্তার(৫৩ থেকে ৩২৮ mg/dL) এবং*পরিবর্তনের গতি (velocity)* দ্বারা পরিমাপ করা হয় । গতকালকের গ্রাফে যে খাড়া নিম্নমুখী রেখাটি দেখা গেছে, তা দ্রুত এবং লক্ষণযুক্ত হাইপোগ্লাইসেমিয়ার উচ্চ ঝুঁকি তৈরি করে।
এই অস্থিরতার মূল কারণ হলো সকালের ইনসুলিনের সময়সূচী: ইনসুলিন ছাড়া সকালের খাবার দিলে রক্তশর্করা ৩০০ mg/dL-এর উপরে চলে যায়, যা পরবর্তীতে অতিরিক্ত ইনসুলিন প্রয়োগের ফলে হঠাৎ হাইপোগ্লাইসেমিয়া ঘটিয়ে দেয় । এটি স্থিতিশীল করতে হলে বেলা ১১:০০ টায় সমস্যা তৈরি হওয়ার পর তা সংশোধন না করে, সকালের দুধ ও খাবারের আগেই দ্রুত-কার্যকরী ইনসুলিন (Lispro) প্রয়োগ করা প্রয়োজন ।
More details of this case report available in the below link👇

No comments:

Post a Comment