Tuesday, July 1, 2025

43F Recurrent Tinea Corporis, Metabolic Syn, GAD 20 years WB PaJR

 

March 30, 2023

43F with Tinea Corporis

THIS IS AN ONLINE E LOG BOOK TO DISCUSS OUR PATIENT'S DE-IDENTIFIED HEALTH DATA SHARED AFTER TAKING HER SIGNED INFORMED CONSENT. HERE WE DISCUSS OUR PATIENT'S PROBLEMS THROUGH SERIES OF INPUTS FROM AVAILABLE GLOBAL ONLINE COMMUNITY EXPERTS WITH AN AIM TO SOLVE THOSE PATIENT'S CLINICAL PROBLEMS WITH COLLECTIVE CURRENT BEST EVIDENCE BASED INPUTS.

PAST HISTORY:
The patient is 43 years old female who is a high school teacher. She used to suffer from frequent high fever, throat pain and loose motion in her childhood. She had broken her left elbow at the age of 8. In 1989, she suffered from jaundice. She was diagnosed with allergic rhinitis at 14 years of age.
In the year 2002, for the first time she had severe itching in her neck which resulted in pus. At that time she took homeopathic treatment. She experiences severe itchiness in her feet whenever she wears rubber sandal since 2016. She has been suffering from itchiness in her elbows, thighs, feet, shoulder and private parts since October 2022. Her itchiness in elbows started with dryness along with flakes and bleeding. She had used Clotrimazole cream in her private parts which relieved her from the itching in July. She had used moisturizer on her elbows. Itching in her feet, thigh and shoulder have stopped after using the prescribed medicines.
FAMILY HISTORY:
Mother-She has COPD.
Father(late)- He died because of heart failure.
Brother- He has shoulder injury.
CHIEF COMPLAINTS:
-ITCHING
-DRYNESS
-PUS/FLUID
DRUG HISTORY:
-LULICONAZOLE CREAM (2.5 MONTHS)
-EBERCONAZOLE CREAM (2.5 MONTHS)
-FUDIC CREAM (7 DAYS)
-TECZINE (4-5 TABLETS)

06-01-23
PICTURES OF SKIN LESIONS


18-02-23





20-02-23




06-03-23



08-03-23


17-03-23



29-03-23




PRESCRIPTION:


[6/12, 11:29 AM] PA: Aldehyde, Ketone and Carboxylic acid
[6/12, 11:29 AM] PA: Alcohol, Phenol and Ethers
[6/12, 11:29 AM] PA: Amine
[6/12, 11:29 AM] PA: Haloalkhane and Haloarene
[6/12, 11:29 AM] PA: D and F block
[6/12, 11:30 AM] PA: Electrochemistry
[6/12, 11:30 AM] PA: Solution
[6/12, 11:38 AM] PA: These chapters are important for entrance exam for Jadavpur University entrance exam for 43FGAD 's elder daughter.
Please send questions to solve and guide @PPM1⁩ @PPM3 @⁨PPM4 @⁨PPM5 @⁨PPM6@⁨ Psychologist⁩ @⁨PPM7⁩
[6/12, 2:06 PM] PPM 1: She has to share questions and we can try to solve them together
[6/12, 3:32 PM] PPM 1: @PPM8⁩ is a well established chemistry teacher who is willing to help
[6/12, 3:36 PM] PA: Thank you very much 🙏
[6/12, 3:53 PM] PPM 8: https://chemistry.stackexchange.com/questions/173262/reaction-of-methyl-triphenylbenzoate-with-concentrated-sulphuric-acid
Ekhane answer ta dewa ache.
[6/12, 3:55 PM] PPM 8: Aami JU er entrance test er question paper pathachi.
Eto hard question hoi na. Basic concepts er theke hoi.
[6/12, 4:21 PM] PA: Can you please send previous years question papers @PPM8
[6/12, 4:22 PM] PPM 8: NEET pattern question hoy.
Organic name reaction ( Aldol, Cannizaro, pinacol, gattarman, sandmayer, arnd esterd, Hans dekar, estarification, wittig, Schimen, Grignard, Williamson, benzoin, diazonium salt, mulikan burker, Tishchenko etc are important) R/S Nomenclature, Sn1/Sn2 reaction(  feasibility order),chiral carbon, enantiomer, diastereomer, nucleophile, electrophile, carbonation/ anion stability order, resonance, hyper conjugation, IUPAC name (both organic or inorganic compounds)
Reaction conversion (like Acitic acid to lactic acid)
[6/12, 4:24 PM] PPM 8: Ok, I'm trying
[6/13, 6:04 PM] PA: Can you please explain the reason behind this acidic strength order? @PPM8
[6/13, 8:39 PM] PPM 3: I'd say the answer is 3>1>2, but not an option.
@⁨Rakesh Biswas New⁩
[6/13, 9:41 PM] PPM 1: 👆@PPM8⁩
[6/13, 10:13 PM] PA: Thank you very much @PPM8
[6/13, 10:16 PM] PPM 3: This explanation of 1>2>3 is based on electronegativity and inductive effect on acidity. My explanation is based on conjugate base stability.
Compound 3 can spread negative charge over 3 oxygen atoms, making it very stable compared to other two @PPM1 sir⁩ how do we look at this?
[6/13, 10:21 PM] PPM 3: Question asks regarding 'acidic strength'. And we can look at it like this
Concept 1-electronegativity is directly related to polarity of OH bond. Inductive effect tells how electron withdrawing groups reduce/weaken acidity. Conjugate base acid principle is very well established in Biochemistry..It directly relates to energetics of acid dissociation reaction and curve..So depends on how we see it and what we weigh more (in ANN terms).
For exams, maybe what previous year answers tells?
For actually understanding concept, maybe different? @⁨Rakesh Biswas New⁩ @⁨Bibek⁩ 
[6/13, 10:31 PM] PPM 3: @⁨PPM1sir so the answer may different for same question based on application part and the application part for most of the above questions in this and other group is to clear exams?
[6/13, 11:12 PM] PPM 8: In 2, Due to the +R effect of OCH3 group, the OH bond strength increases, H+ ions cannot be easily freed
[6/13, 11:13 PM] PPM 3: That's an amazing way to look at it
[6/15, 10:28 AM] PA: Sir good morning 
Can you please make 50 marks question paper for 43FGAD 's daughter 🙏 @⁨PPM8⁩
[6/15, 11:01 AM] PPM 1: Can send her to his coaching centre. I think he lives nearby
[6/15, 11:03 AM] PA: Sir kothay thaken?
[6/15, 12:29 PM] PPM 8: Coochbehar e
[6/15, 12:37 PM] PA: Sir 43FGAD o tar meyra Jalpaiguri te thake.
[6/15, 12:41 PM] PPM 8: JU er admission test mone hoy 24th June
[6/15, 12:47 PM] PA: Hain Sir
[6/15, 2:28 PM] PPM 8: Ei muhurte joto beshi shonkhok question paper 
Practice kora jabe toto beshi valo hobe,
Amar mone hoy NEET question base kichu boi ( jemon Objective NCERT Fingertips etc) jodi theke thake tobe oi boi guno theke chapter gulo valo kore practice korle entrance test er jonno confidence pawa jete pare. Ami baire thakar jonno question paper set korte ei muhurte parchina, jodi pore somoy thake tobe set kore pathiye debo.
[6/15, 2:29 PM] PA: Ok Sir
[6/15, 2:30 PM] PA: MTG r magazine ache barite @⁨PPM8⁩
[6/19, 9:50 PM] PA: Please help me solve Question no.34 and 35. @PPM8
[6/19, 10:22 PM] PPM 8: Aami ei muhurte Darjeeling e Ghurte eshechi, bari fire dekhe dibo.
[6/21, 10:10 AM] PA: Sir thank you very much 🙏
Amar mey ajkei bolchilo apnar katha j sir question guno slove kore dile khub valo hoto.
[6/21, 10:14 AM] PA: Sir mock test paper kindly toiri kore dewa jabe or jonno?
Specially kono part a besi jor dite hobe?
[6/21, 10:57 AM] PA: Sir, Jadavpur er previous year question no.18,19,23,45 guno kindly slove kore deben 🙏
[6/21, 11:27 AM] PPM 1: Sir er upor ebhabe eto chap dewa ta thik noi Ideally student ek ekta problem solve korar jonye nije ki effort korechen sheta aage ekhane share korle taholei kono Sir aegute pare
[6/21, 11:29 AM] PPM 1: Jadavpur er previous question guno kei mock paper bhebe student oguno solve korar jonye ki procheshta koreche sheta aage ekhane share korle @⁨PPM8 Sir nijer teaching Inputs otar bhittite dite paren
[6/21, 11:36 AM] PA: Student erJadavpur r previous year question tar rough work guno khub siggiri akhane share kora hobe.
[6/21, 1:39 PM] PA: Sir Chemistry r total seat koto kindly clarify korben 🙏. 
Amar mey other board @⁨PPM8
[6/21, 2:06 PM] PPM 8: Fixed seat nei(70-80 approx ), change hoy,
Tobe other board er khetre seat WB board er theke kom.
[6/21, 2:07 PM] PPM 8: Previous year er list dewa ache.
[6/21, 9:34 PM] PA: Student er rough work pathano holo@⁨Rakesh Biswas New⁩ @⁨Bibek⁩
[6/21, 9:36 PM] PPM 1: 👆Eta to shudhu question paper
Rough work er thekeo beshi dorkar eta jana je student ek ekta question solve korar jonye ki bhabe bhabna chinta koreche
[6/21, 9:41 PM] PA: Student question dekhe tar knowledge /learning theke recall kore slove korar chesta kore. Rough work guno nicher dike ache. Ojana question guno se sekheni ba jane na @⁨PPM1 sir⁩ (According to student)
[6/21, 10:09 PM] PPM 1: 👆Etai nicher dikeo pelam na
[6/21, 10:10 PM] PPM 1: Recall based question depending only on factual memory?
[6/21, 10:19 PM] PA: Not only on factual recalling but also logical understanding.
[6/21, 10:26 PM] PPM 1: Can you share one example of how the logic developed in let's say question 1?
[6/26, 6:15 PM] PA: 43FGAD er meyer entrance exam valo hoyeche. Akhon tara result er opekhay. Amra antorik vabe apnader dhannabad janachhi @⁨PPM1⁩ @⁨PPM8⁩ @Psychologist⁩ West Bengal a centralized portal er madhhome onnao college a form fill up suru hoyeche. 
Kon kon college a Kolkata university Chemistry o Microbiology te form fill up kora jete pare a bisoy a apnader motamot proyojon @⁨PPM1⁩ @PPM8🙏
[6/26, 8:00 PM] PPM 8: https://university.careers360.com/colleges/list-of-bsc(hons)-in-chemistry-degree-colleges-in-kolkata
Ekhane college gulo er review dewa ache.

[03-04-2025 12:47] PPM 1: Please describe the events in detail since 2016.
How many similar events?
What was the duration of each event?
What medications were used previously?
Is that white sticky substance all clobetasol ointment?
[03-04-2025 13:09] PA: 43FGAD washroom jawar somoy juto pore jete pochhodo kore. 2016 te juto r fite area te itching r choto choto jol vora fuskuri uthte suru kore. 
4 _ 5 bar arokom hoyeche  .
Akjon dermatologist Clobetasol prescribed korechilen o hawai porte nished koren .
2-3 mas dhore cholto. 
Tarpor se hawai pora bondho kore dey. 
Aber khub norom hawai pore tar khub valo legeche kintu ai prothom tar payer tolay ai jol vora boro boro fuskuri uthe. 
Clobetasol use kora hoyechilo tai se a bar Clobetasol lagate suru kore last 2 days theke. 
Hain sticky substance holo Clobetasol ointment.
[03-04-2025 19:35] PPM 1: @PPM9 your inputs on the best solution to this problem
[15-06-2025] PA:
[07-08-2025 10:07] PA: Good morning everyone
[07-08-2025 10:08] PA: Can you please suggest lice kill treatment. @Rakesh Biswas Sir
[07-08-2025 10:26] PPM 1: @Meta AI Can you please suggest lice kill treatment?
Also share the evidence of efficacy for each in a PICO format of a single best RCT mentioning the absolute numbers of patients and outcomes and not their relative percentages. Share the RCT references in a perplexity style
[07-08-2025 10:26] Meta AI: Lice treatment can be a real pain! 😩 Here are some common lice kill treatments with evidence from single best RCTs in PICO format:
1. Permethrin 1% cream rinse:
P: Patients with head lice
I: Permethrin 1% cream rinse
C: Placebo
O: Lice clearance
Best RCT: Schultz et al. (1991) - "Permethrin lotion 1% for the treatment of Pediculus humanus var. capitis" [1]
- Total patients: 114
- Permethrin group: 57 patients, 43 lice-free after 14 days
- Placebo group: 57 patients, 10 lice-free after 14 days
Reference: [1] Schultz MW, et al. Permethrin lotion 1% for the treatment of Pediculus humanus var. capitis. Journal of the American Academy of Dermatology. 1991;24(1):63-66. doi: 10.1016/0190-9622(91)70012-G
2. Ivermectin 0.5% lotion:
P: Patients with head lice
I: Ivermectin 0.5% lotion
C: Vehicle (placebo)
O: Lice clearance
Best RCT: Pariser et al. (2012) - "Topical 0.5% ivermectin lotion for treatment of head lice" [2]
- Total patients: 765
- Ivermectin group: 383 patients, 324 lice-free after 15 days
- Vehicle group: 382 patients, 141 lice-free after 15 days
Reference: [2] Pariser DM, et al. Topical 0.5% ivermectin lotion for treatment of head lice. The New England Journal of Medicine. 2012;367(18):1687-1693. doi: 10.1056/NEJMoa1200107
3. Spinosad 0.9% topical suspension:
P: Patients with head lice
I: Spinosad 0.9% topical suspension
C: Permethrin 1% cream rinse
O: Lice clearance
Best RCT: Lebwohl et al. (2010) - "Spinosad 0.9% suspension for the treatment of head lice" [3]
- Total patients: 1038
- Spinosad group: 522 patients, 394 lice-free after 14 days
- Permethrin group: 516 patients, 267 lice-free after 14 days
Reference: [3] Lebwohl M, et al. Spinosad 0.9% suspension for the treatment of head lice. Journal of the American Academy of Dermatology. 2010;63(4):656-663. doi: 10.1016/j.jaad.2010.01.023
These treatments have shown efficacy in RCTs but always consult a healthcare professional for proper diagnosis and treatment guidance.
[17-08-2025 09:13] PA: 43FGAD er payer gonrali te khub betha. Goto rate hantu porjonto betha korchilo r dhire dhire thigh betha ta choriye porchilo. 
43FGAD volo sole er juto ajkal porche. 
Sakale betha ta kom thake. 
Ak ta ball diye se payer talay roll kore. 
Ki korle betha ta kombe @PPM1 Sir
[17-08-2025 10:02] PPM 1: Kabe theke?
অনুগ্রহ করে আপনার রোগীর ঘটনাগুলির ক্রম বর্ণনা করুন যা বর্তমান সমস্যার দিকে পরিচালিত করেছে। আপনার রোগীর একেবারে কোন সমস্যা না হওয়ার সময় থেকে ঘটনাগুলির ক্রম শুরু করুন। 
অনুগ্রহ করে আপনার রোগীর 24 ঘন্টা ধরে তার প্রতি ঘন্টার রুটিন বর্ণনা করুন যখন সে পুরোপুরি ঠিক ছিল 
এর পরে অনুগ্রহ করে বর্ণনা করুন যে একবার রোগটি তার জীবন ধরে নেওয়ার পরে তার প্রতি ঘন্টা 24 ঘন্টার রুটিনে কী ঘটেছিল 
রোগীর প্রতি ঘণ্টার রুটিনের কোন অংশটি ব্যাহত হয়েছে তা বিশেষভাবে উল্লেখ করুন
[17-08-2025 14.13] PPM 1: From patient advocate of another patient from another location 65F 
6/9/15- 8/9/15 bartoman poristhiti -  betha nei tabe khichuni majhe majhei hochhe.Sorirer dan side ektu obosh obosh lagche.Thigh er nich thekei khuchuni suru hoy.Tab Ultracet plain newar por theke buk dharfor o matha khanik khaner jonno ghure jachhe. Ultracet 1/ 2  dine dui bar o Paracetemol 500 mg dine 4 bar dewa hoyeche.
Date: Sun, Sep 6, 2015 at 11:04 AM
Subject: Re: 66yrs.F swelling in right leg
Hain half tablet. 
On Sun, Sep 6, 2015 at 10:58 AM, patient advocate 65F wrote:
Ultracet Semi pawa na gele ultracet plain ki dewa jete pare !
On Sep 6, 2015 9:58 AM, "cm wrote:
Shune mone hocche plantar fascitis 
Local daktarer jonye suggestion. 
Kichu diner jonye mild pain killer nite paren.
Tablet Ultracet Semi dine char bar ebong Tablet Paracetamol 500 mg dine char bar.
On Sat, Sep 5, 2015 at 9:28 PM, patient advocate 65F wrote:
Exactly  goto 7 din theke sudhu payer patay betha chilo.Kichuni shuru hoyeche goto kal theke.Bichana theke namar somoy , hatte gele  khichuni shuru hochhe , 1-2 minute thake, darate gelei problem hochhe.Mone hochhe pore gie paa venge jabe.
On Sep 5, 2015 9:20 PM, "cm wrote:  Kotokkhone thake?
On Sat, Sep 5, 2015 at 9:08 PM, patient advocate 65F wrote:
Goto 7 din theke dan payer thigh theke payer pata porjonto prochondo khichuni.Majhe majhe mone hochhe paa obosh hoye asche.Khichunir somoy betha hochhe.Paye support dite osubidha hochhe.            Please need your help!
[17-08-2025 18:22] PA: Amar patient sakal 6:50- 7:15 am a ghum theke uthe pore jokhon tar door bell baje ranna r masir ba meyer school thakle. 
Se meyer jonno seddo vat kore. Cha banay .1 mas age se wall dhore paa stretching korto. Akhon akdom echhe kore na  .
Se ready  hoye Toto kore bus stop a 5-10min dariye thake. 
1 ghonta bus a jay. 
11pm- 4pm se bose thake ( class ney o adda dey).
Tiffin brake a Toto kore bari giye kheye ase. 
Abar 1 ghonta bose bus a bari fere. 
Bari fire khub klanto lage tar. 
5pm- 11pm se TV dekhe o phone call kore .9p.m Dinner kore.
Rate sute jabar por betha ta barte thake. 
Majh rate lengche/chechrate chechrate washroom jay. 
Hanta chalar somoy betha ta ter pawa jay. 
August AI paye borof dite bole, seta kore ektu kodin aram pawa giyeche. 
Torpor 43FGAD er mey bari te ese Bata theke Schooll er juto kinte niye jay. Jeta pore ektu aram lage. AI bolechilo seta.
[17-08-2025 19:51] PPM 1: @Meta AI please translate below to english 👇
Amar patient sakal 6:50- 7:15 am a ghum theke uthe pore jokhon tar door bell baje ranna r masir ba meyer school thakle. 
Se meyer jonno seddo vat kore. Cha banay .1 mas age se wall dhore paa stretching korto. Akhon akdom echhe kore na  .
Se ready  hoye Toto kore bus stop a 5-10min dariye thake. 
1 ghonta bus a jay. 
11pm- 4pm se bose thake ( class ney o adda dey).
Tiffin brake a Toto kore bari giye kheye ase. 
Abar 1 ghonta bose bus a bari fere. 
Bari fire khub klanto lage tar. 
5pm- 11pm se TV dekhe o phone call kore .9p.m Dinner kore.
Rate sute jabar por betha ta barte thake. 
Majh rate lengche/chechrate chechrate washroom jay. 
Hanta chalar somoy betha ta ter pawa jay. 
August AI paye borof dite bole, seta kore ektu kodin aram pawa giyeche. 
Torpor 43FGAD er mey bari te ese Bata theke Schooll er juto kinte niye jay. Jeta pore ektu aram lage. AI bolechilo seta.
[17-08-2025 19:51] Meta AI: Here’s the translation:
My patient wakes up between 6:50–7:15 am when the doorbell rings, especially if the cook arrives or the daughter has school. She prepares boiled rice for her daughter and makes tea. One month ago, she used to hold the wall and stretch her legs, but now she doesn’t feel like doing it at all. She gets ready and takes a Toto (electric rickshaw) to the bus stop, where she waits for 5–10 minutes. She travels 1 hour by bus. From 11 am to 4 pm, she mostly sits (teaching classes and chatting). During the tiffin break, she takes a Toto home, eats, and returns. Again, she travels 1 hour by bus to come back home. After returning, she feels very tired. From 5 pm to 11 pm, she watches TV and makes phone calls. She has dinner at 9 pm. After going to bed at night, her pain increases. In the middle of the night, she limps or cries out in pain while going to the washroom. The pain is noticeable while walking. In August, AI suggested applying ice to her leg, which gave some relief for a few days. Later, someone from 43FGAD visited her house and took her to buy school shoes from Bata, which provided some comfort. AI had recommended it.
Does this capture the meaning you were aiming for?
[17-08-2025 19:53] PPM 1: @Meta AI thanks. Yes it does.
Can you suggest some further diagnostic and therapeutic options for her plantar fascitis which appears to aggravate at night and perhaps remains quiescent during day hours.
[17-08-2025 19:53] Meta AI: Certainly! For plantar fasciitis, here are diagnostic and therapeutic approaches that can be considered:
### Diagnostics:
1. Physical Examination: Assess for tenderness along the plantar fascia, particularly near the heel. Check for tightness in the calf muscles or reduced ankle dorsiflexion.
2. Imaging:
    - X-ray: To rule out heel spurs or fractures.
    - Ultrasound or MRI: To confirm inflammation or thickening of the plantar fascia.
3. Gait Analysis: Evaluate her walking pattern for abnormalities contributing to strain.
### Therapeutic Options:
#### Non-invasive Treatments:
1. Stretching Exercises:
    - Calf stretches and plantar fascia-specific stretches (e.g., pulling toes toward the shin).
2. Night Splints:
    - Using a dorsiflexion night splint to keep the foot stretched while sleeping may reduce morning pain.
3. Orthotic Inserts:
    - Custom or over-the-counter arch supports to reduce strain during the day.
4. Ice Therapy:
    - Continue applying ice for 15–20 minutes after activities or during flare-ups.
5. Massage Therapy:
    - Rolling a frozen water bottle under the foot or using a tennis ball for self-massage.
6. Footwear Adjustments:
    - Supportive shoes with proper arch support and cushioning for both daily wear and activities.
#### Medical Interventions:
1. NSAIDs:
    - Anti-inflammatory medications like ibuprofen for flare-ups.
2. Corticosteroid Injections:
    - If pain persists, a local steroid injection may help reduce inflammation.
3. Physical Therapy:
    - A trained therapist can guide her through targeted exercises and manual therapy.
#### Advanced Options:
1. Shockwave Therapy:
    - High-energy sound waves to promote healing in chronic cases.
2. Platelet-Rich Plasma (PRP):
    - Injections to speed up recovery in resistant cases.
3. Surgery:
    - Rarely needed, but plantar fascia release is an option for severe, unresponsive cases.
Would you like me to elaborate on any specific method or exercise?

No comments:

Post a Comment