[5:52 pm, 01/02/2026] PaJR Health: I have found a relevant paper by Emma Ahlqvist on the classification of diabetes:
*Phenotypic and genetic classification of diabetes.*
[Diabetologia. 2022 Nov;65(11):1758-1769.](https://pubmed.ncbi.nlm.nih.gov/35953726/)
*PMID:* 35953726
*Abstract Quote:*
"The historical subclassification of diabetes into predominantly types 1 and 2 is well appreciated to inadequately capture the heterogeneity seen in patient presentations, disease course, response to therapy and disease complications. This review summarises proposed data-driven approaches to further refine diabetes subtypes using clinical phenotypes and/or genetic information. We highlight the benefits as well as the limitations of these subclassification schemas, including practical barriers to their implementation that would need to be overcome before incorporation into clinical practice."
This paper is a review that summarizes data-driven approaches to refine diabetes subtypes using clinical phenotypes and/or genetic information, addressing the limitations of the traditional type 1 and type 2 classification. It discusses the benefits and limitations of these new classification schemas and the practical barriers to their clinical implementation.
[1:14 pm, 02/02/2026] cm: Signposting another Narketpally sign with imaginary pillow due to OPLL secondary to fluorosis. He also has metabolic syn and the triad of Fl, C2H5OH and C6H12O6 mediated toxic damage
[1:28 pm, 02/02/2026] cm: Can add this to the Narketpally syn ProJR in PaJR blogspot @cr
[1:30 pm, 02/02/2026] hu2: This triad was presented at Osmecon recently wasn't it?
[1:32 pm, 02/02/2026] cm: None of our students wanted to present it there 😅
[1:33 pm, 02/02/2026] cm: It needs to be consolidated with a meticulous collection and archival of a substantial number of cases and hopefully @hu131 will lead the way this year
[1:38 pm, 02/02/2026] hu2: This is how this message was auto saved to the database
"The [REDACTED] patient's presence on an examination table and the clinical environment are consistent with ongoing management of complex conditions, including Ossification of the Posterior Longitudinal Ligament (OPLL) secondary to fluorosis, metabolic syndrome, and the triad of Fluoride (Fl), Ethanol (C2H5OH), and Glucose (C6H12O6) mediated toxic damage, as referenced in the provided context (https://pubmed.ncbi.nlm.nih.gov/40674544/). The patient's prone position directly on the table surface (without a physical pillow) may be related to comfort or a specific examination posture for spinal conditions associated with OPLL."
[1:38 pm, 02/02/2026] hu2: Looks like it auto redacted the word Narketpally here!
[1:43 pm, 02/02/2026] hu131: Looking forward to it sir
[1:47 pm, 02/02/2026] cm: I guess it has been through a stringent training program!
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